lEFT HAND DRIVE

Are you kidding Vince?

Just put your hands behind your back and click! lol

Well, thought I would add something as plenty have looked without comment. Interesting question actually...

The Yashica Samurai half frame film camera of the 1980s is one rare example of a left handed/ single handed camera. 

I'm left handed and could never see myself using a left handed camera being so used to a right handed layout, and being so used to Nikon ergonomics, can use any of my Nikons faster than my Canons, where I have to think a bit more of their different layout. In many cases this wouldn't really matter too much but where things are moving/happening fast, then for me, it's Nikon all the way, particularly the D3. A left handed version would be hopeless for me, and Canon shooters would likely find the same thing in reverse if they picked up a Nikon.

Perhaps there's one possible answer in Vince's case if someone has limited or no use of their right hand. Using a compact to keep the weight down, shoot with the camera upside down, using the thumb to operate the shutter button now on the bottom left side.

There's also, if the camera has the facility for it, using a cable/electronic release. Supporting the camera might then become the real problem as the case might be.